rabphilin

rabphilin
Receptor (704 amino acid residues) for the small GTP-binding protein rab3A that is implicated in regulated secretion, particularly of neurotransmitters. The N terminal region interacts with rab3A, the C terminal domain interacts with calcium and phospholipid, and rabphilin is found in association with sites of exocytosis in neurites. There are indications that rabphilin may inhibit GAP-activated GTPase activity of rab3A.

Dictionary of molecular biology. 2004.

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